ZINCOTASE film-coated tablets, Zinc deficiency, zinc bis(hydrogen-DL-aspartate), ZINCOTASE

Pack size:50 pieces Dosage form:Film-coated tablets

Zinc deficiency, zinc bis(hydrogen-DL-aspartate), ZINCOTASE

Active ingredient: zinc bis(hydrogen-DL-aspartate).
25 mg zinc per film-coated tablet

Application: Zinc deficiency conditions that cannot be remedied through nutrition.

For information about risks and side effects, read the package leaflet and ask your doctor or pharmacist.

Dosage form, pack size: 50 film-coated tablets (N2).

Zinc deficiency, zinc bis(hydrogen-DL-aspartate), ZINCOTASE

eliminates zinc deficiency

• Adequate zinc status is important for the immune system
• High doses of zinc can shorten the duration of a cold
• Prevent colds – avoid zinc deficiency

ZINKOTASE film-coated tablets
To correct zinc deficiency states that cannot be remedied through nutrition and during therapy with penicillamine.

ZINKOTASE contains no yeast and is gluten, lactose and gelatin free. Suitable for vegetarians and vegans.

The importance of zinc has been scientifically proven. Without zinc, the human immune system cannot perform its functions properly. The body needs the trace element to form defense cells, control immune reactions and ultimately kill pathogens. If there is a zinc deficiency, the organism lacks the weapons to fend off attacks from viruses and bacteria. The result can be an increased susceptibility to infection. Cough and cold germs then have an easy time of it - especially in the cold, humid season.

^© biosyn Arzneimittel GmbH

A cold lasts seven days with treatment and a week without it? Some studies now show that this is not always true. Even if you notice the first scratchy throat or runny nose, zinc can help. In scientific studies[1-4], taking high doses of zinc shortened the duration of a cold by two to three days. The typical symptoms such as coughing, hoarseness, runny nose and muscle pain also decreased. Less than half of the patients still had a cold after seven days.

Sufficient supply of zinc - as part of cold therapy

^© biosyn Arzneimittel GmbH

Zinc is necessary for many body functions
Zinc not only protects the body against infections: it is a component of more than 300 human enzymes that are involved in the digestion and utilization of fats, proteins and carbohydrates. It also influences the structure of the genetic material and cell growth.

Zinc contributes

• to normal function of the immune system
• to normal acid-base metabolism
• to normal cognitive function
• for the normal structure of the genetic material
• to normal fatty acid metabolism
• to normal protein synthesis
• to maintain normal bones, skin, hair and nails
• to protect cells from oxidative stress
• for normal cell division

Groups at risk of zinc deficiency
Zinc is an essential trace element that is normally sufficiently ingested with food. However, due to changing eating habits, increased consumption of fast food and ready meals, high alcohol consumption, but also because of some voluntary diets or vegan diets, more and more people are consuming too little zinc. Experts assume that about a third of the population does not have an adequate supply of zinc. Foods high in phytine can also reduce zinc absorption. These include, above all, whole grain cereals, beans, nuts, brown rice and corn.

Competitive athletes, pregnant and breastfeeding women, for example, have an increased zinc requirement. The same applies to people with a chronic intestinal disease, diabetes or rheumatism. In older people, the ability of the intestinal mucosa to absorb zinc into the blood also decreases. Certain medications also hinder absorption or increase the need, such as cortisone, blood lipid-lowering agents, stomach acid-binding and dehydrating agents.

How can a zinc deficiency become noticeable?
A zinc deficiency can only be clearly detected through a laboratory blood test. However, there are a number of symptoms that - in addition to the increased susceptibility to infections - can indicate a zinc deficiency:

• Fatigue and lack of drive
• declining physical performance
• persistent states of exhaustion
• depressive mood
• brittle nails
• dry, flaky skin
• Wound healing disorders

Zinc deficiency can also lead to impaired fertility, growth retardation and anemia.

^© biosyn Arzneimittel GmbH

How much zinc the body needs
The German Society for Nutrition (DGE) currently recommends a daily intake of 10 milligrams for men and 7 milligrams for women. This applies to healthy people, if there is no special need.

Zinc deficiencies can generally be compensated for through a balanced diet: red meat, cheese, nuts, seafood and shellfish are good sources of zinc. However, many people have an unbalanced diet and can therefore suffer from a zinc deficiency without realizing it. Then you can cover your zinc needs with medicines, such as ZINKOTASE from biosyn. One ZINKOTASE film-coated tablet contains 25 milligrams of zinc. The coupling to the body's own amino acid aspartate ensures that the trace element is particularly well absorbed by the organism.

ZINCOTASE is suitable for vegetarians and vegans.

• gluten free
• lactose free
• without yeast
• without gelatin

biosyn Arzneimittel GmbH
Schorndorfer Str. 32
70734 Fellbach


Literature
1. Hemilä H. Open Respir Med J 2011; 5:51-8. Zinc lozenges may shorten the duration of colds: a systematic review.
2. Science M et al. CMAJ. 2012 Jul 10; 184(10): E551-61. Zinc for the treatment of the common cold: a systematic review and meta-analysis of randomized controlled trials.
3. Hemilä H, Chalker E. BMC Fam Pract. 2015 Feb 25; 16:24. The effectiveness of high dose zinc acetate lozenges on various common cold symptoms: a meta-analysis.
4. Allan GM, Arroll B. CMAJ. 2014 Feb 18; 186(3):190-9. Prevention and treatment of the common cold: making sense of the evidence.
5. Kurugol Z, Akilli M, Bayram N, Koturoglu G. Acta Paediatr. 2006 Oct; 95(10):1175-81. The prophylactic and therapeutic effectiveness of zinc sulphate on common cold in children.
6. Vakili R, Vahedian M, Khodaei G, Mahmoudi M. Iranian Journal Of Pediatrics. 2009 19(4), 376-80. Effects of Zinc Supplementation in Occurrence and Duration of Common Cold in School Aged Children during Cold Season: a Double-Blind Placebo-Controlled Trial.
7. Prasad AS. Adv Nutr. 2013 Mar 1; 4(2): 176-90. Discovery of human zinc deficiency: its impact on human health and disease.
8. Black MM. J Nutr. 2003 May; 133(5 Suppl 1): 1473S-6S. The evidence linking zinc deficiency with children's cognitive and motor functioning.
9. Petrilli MA et al. Front Pharmacol. 2017 Jun 30; 8: 414. The Emerging Role for Zinc in Depression and Psychosis.
10. Villagomez A, Ramtekkar U. Children (Basel). 2014 Sep 29; 1(3): 261-79. Iron, Magnesium, Vitamin D, and Zinc Deficiencies in Children Presenting with Symptoms of Attention-Deficit/Hyperactivity Disorder.
11. Maxfield L, Crane JS. Zinc Deficiency. [Updated 2018 Mar 20]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2018 Jan